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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4213aadc00c5506dcec684fbb5f7b3d7a2f2bb73d98299abd15b384d4da8ce71' 
  AND token = '8P4qVlVgWVvCQl8XyXHTXL/pCaG3L7+EW0nVotR7fQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}