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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd6600c4b914c90b47e98384c40d275e1a6119838d4b4be3d4e2501a39f9bbc' 
  AND token = 'w3nNSfjqoDLx/oeaaoOL4mpTyKTaaosbboL6HWlkuMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}