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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a2720ba4648b4f3dbeb4e38d9b836858f8fbdbda70a94943396d4a0944f2c5' 
  AND token = 'NvELTNGwEtrN5l2QF+r6iendU5fwV4YXTMH/0qFWMTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}