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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489e3463e406d6b65b8ffef8d4691d05d202e306a70b116c73ae1d1a284e6cb1' 
  AND token = '1fmPk3qdF2O9DYVhV1ZpO3DBKxoaoWLHCijaMtmT2vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}