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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c043d5ab2a473262bc39ae9165093a089c7f2c1992960c51e9d2c659da155c' 
  AND token = 'QI9WLMCz2QKmzCw94eURGykc1OJv42wikLUdl8c3VTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}