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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db374888337ab1bd164d66ab0873f81f1f1683e4c571ef5aeddee5d6b9289853' 
  AND token = 'v9XxFDFcyS/LDOaqbYnqMQUhllh+87HHtCmyCoHLJEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}