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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f929eeda8950058760dbbd3e5261ff99a268512c7208903c676b6483469c87' 
  AND token = 'i+OsMK4y6kQntOuwgnI0NVLyS9VBzui/8L1a6Zu8jb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}