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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37197c42c51bbd693b841e83f79f62c7c57bf492b9351b8599cf63c021ea1d60' 
  AND token = 'c11OH6etId6dpGGGScK4h+viTxgX46z6GH/g/4xwm8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}