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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9b113e9fe76131007f0bb800770e289dbc2ec1969e3ca0e7e932172f691442' 
  AND token = 'oR74wWrmUtmbdXvVubz5cX7XYI29CYQ1oTSWRCVBo9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}