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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b21c4734d1f6431937a503bb67f40e1203b0725121f0390459f94d5222e30d0' 
  AND token = '4iMPJNdU51kkZeRfBakDknD76UZNVfdfzpQGMrn7/t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}