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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b280cf2c54c304982e95befe12ce68892f24529843f77bd279efb2a3e6fa25b' 
  AND token = '5xFgv1kZ2aEYwyAzBhXfdu45Y2RFJ+Qx9dOn5DFOPbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}