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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8575331439e61d5f534417b10f55ba98fb86dc0a4e17c060b635451b40d127' 
  AND token = 'exeGbQy5RSeR/X98lsMI21rQgVAwHYbwpHdsqoMpGiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}