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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e674105b4410f6f7454ec444728c6c316fea0c6107ab3d8cfa06ee1113f0007a' 
  AND token = 'XYIr4YlDa3nJVoL1gJGda2rNJ93TQbKHMS0gFXb5yyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}