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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '660b12fb6e1296a2780e9099db9939cfa038effb9805f9a145fd6d4940a92463' 
  AND token = 'hG1gd6ZzXnRhh5KtmdkbikOvJ1eVKTBvKwIPwXX9La4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}