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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d957912ee29117094c37846721517257c1b8054dbdc9c806adaad6090b7b3bb' 
  AND token = '+hsxu3dcyIObIRsszYV2z+8dBU8kwMETVdufCjbOhyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}