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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dc99d223a0c1d3de43d0e3f20f7e7f1ecd2fe37ad27b06e31e3f8a3fc4391e' 
  AND token = 'HPikvBXM5thsbSxOKij39fLmJQUFaeMV/ti+7lGnrNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}