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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6118dc0cd9d3e39e683882b49bd1974a2015c00ab32c131820c08dd0bb9b4d6' 
  AND token = 'LF4oZJeE3MhjEWgBUmPnFhmbbTu1DL1MGI/pLKPOEwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}