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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb80bf9ae58800700ae115eb86b5cf494730646b68c66c19a5bcd496355af16e' 
  AND token = 'qO4vYBV9FRcFLWhs/u9pEFtz+hmhoEEO85zNM6UrOr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}