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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2010e00c9cf53b35c5daf993206eaaebcfa3a6f540bf0feb775433b61380cead' 
  AND token = 'x4Ic9UItzmry6KydlXvKwefZs+Hjx5VaBFOVmMVSZos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}