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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcc9f40636482445d515e13b79e381eb626394c931d72c9378bf0ba4cfeae7c' 
  AND token = 'V+R93oT/tSav1iXkD06t06DdsooPY4/bNEyWnLyrTSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}