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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f4d2ab0d34860812f90d50a64390dfd473e4fef14b4cb2a98d6533e3b3a4f20' 
  AND token = 'hlgLmXjMc/ivsYE8JFdITAVSJiZXNqTS0GUlXyNbT2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}