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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4737ac8cacd836e25482da78ce03239a8857e13c60bddfc7360410c1f0febe82' 
  AND token = 'WBDSaR8ZJDJ7ToH8IXUStItd1Oiy2v7GkAE2c4c0akw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}