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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386d129b1e86ad9369c564333d12bf2e153de6f25cfb22b1d7f298d20f823df1' 
  AND token = 't0S9Xbg533ClSCfQfRCa0t64viiWU4IBcqPN9Zp9H7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}