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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd943e8986cf811feee51b786fa3cdee1c50db0d9ed9f1edde6f7c5f1c0835f58' 
  AND token = 'bv/vJ3nvoC5BRBnpATnI+RXFGxbhAECzQ8MGtJqjRQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}