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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2874f76d27b42e2219eee6f62659facc66d7f80b0184ef654e90e9c4bc21071b' 
  AND token = 'e0z1uX8EF4aaZZ5NMBqw09a05JfU+5WLB0AuPJ17ENQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}