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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d1f4d1d2b9955d7c46c7d7fdf35a72822a688ed3e2a54985fd734ff78adf38' 
  AND token = 'a+D3yXn09Z9xF2LaLJuTaAxy36CGiF4qxC3Q2/8xRT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}