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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46994e8a70838298d11579ae4b4d3e3cc325d87d235a859e75150cbce7b896d' 
  AND token = 'cX6KtpP81hanbvmN2E8dTi37/VjbTqFj27MzcThPE8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}