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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ef58e939097d8b15e7c06a0f2b1b863db2a23f45cba32344b827d2bd678c84' 
  AND token = 'LGny7abwrszBuOouq0gq+DfMAAzMR7p6zBegyQJ+ne0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}