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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b4c0b8a3aa5b9150305564254bfe8104960fead125203ec8c8c55b4fc14c63' 
  AND token = 'Vj8YJGN6UXaze9A5NDQM5bFVww8nM//sJgUVc1fFNjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}