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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c2b9e3b2ccd0f5119bbcd7eff52465ca3aec141e3a5776316d6885f651afab' 
  AND token = 'eLOf7h28AXKzy7/TXqEm44B2qO9VtxtWmcKAdxsPUtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}