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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebf95a71493c999cd58982708cc5f4e610b39efb90d173de24b0a9e0635b3a25' 
  AND token = 'VaEv2dCMsRjLmGZpB7fhGz1EL81GiRpog9Xh6mBNMp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}