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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bb4e55dfd82153870ae11645444bcc7b4391e3c34adcecc5da32ffdcd9e89e' 
  AND token = 'X6wtf305yVKkcux/302QLgqnjVSSjzyHYNv/4v0pydc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}