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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e477b0700f57256ffda84ddf9ca8324d76705c45478e20ef9402f21f151824a5' 
  AND token = 'AnIPKow+pZkjl6pbBnQr6oloyKwZdM8Cb6HgAvdJm6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}