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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc567353be0d80d10a26446a2a9a39121d78af603c11873b814051e4c8f9589' 
  AND token = 'zAv3qH99Dhck/4rsl9umesu6L0WT/G5cn7w8fErJEq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}