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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77762f7c5a6e649a1065d382412d889f0a4a727e8c94357599b41b73a4aab527' 
  AND token = 'WX/nCaaWeS+koQiDJVmPg36L90NQyMTH8TEEzHX8yCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}