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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1053c9f6fd1cc2bc9e8d2c784e4a7c026af90fadf5de3b99ccc7b951c23c8830' 
  AND token = 'azf9NwUsqkWo0JME9g9MnaoipxYS6mIKdwprcqZKuQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}