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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd2d3bf6c63b2d2169e8bb06dca89b110b0217d1ee2c39d0ca8990014e00c9a' 
  AND token = 'GYo053MJMavhUEuI3UkqLqhirx+LcAPUMbFjwymYrRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}