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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82185807a422e6f090f49f3ebe91d3bfadec442e7b5d52670e0ac0dd17282f6a' 
  AND token = '+H+R2CszImao2xrZdnY8y1Zsw91PXWMgptXOEKcaurs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}