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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4589e564e02158ec543efc1b41e12eb234ef101e65913a3c7b9982a42776f41c' 
  AND token = 'YEl6eUK7fpbhv0N5WFci7LSI2E2Q8JY2CdM+MFhw2J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}