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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dde78a41dd2bbc74c0d1762068ad230ec90a0ca7290a79ad250e664dd06660' 
  AND token = 'sr9c7iuXiFSslUrdZ4E4ItgDHrXYfXFr+A2rz3LKd60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}