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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cdf4d7dd59a8899d7af00f751ea7c3d623dc531b5231d23125815e50f0a62d2' 
  AND token = 'ME+v9AtvbPZNyoZPSNAQFvD+sYdSeqmMreIKGkzEAEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}