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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1626ad45a205708408ae3cd709a8e7b0caed2d2c4591b2402cc1971c01b4d3df' 
  AND token = 'Iy1HqDHUYlWdSjwq6eSS1pvXaRrD1kxk1bPdWfs9tSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}