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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a959580b0c1f9c6bacd7bce0890a41d468db3722efec5e86c875994b4c8b3c67' 
  AND token = 'EwxKfT4tLe2dZxM6t0S9bQEdSQEN3UmCgl5CsxQ/hRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}