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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0025e1ef569314d1eaf2a7abb65cb269527acc2d25f7af0b9a08e1de79e34e4' 
  AND token = 'gaiikWlajYt6QU7WWzdQjxsZ3KT7XRT/mfFZYTJ3vDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}