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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01f1e7e7f3ce5a508d4913a6f95fc5a1953602c933a936a13956506655e8190' 
  AND token = 'atsBYYS5eZgnA8RjEqojqaA3SY2KXTy9RDx2AK9FEas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}