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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1c1a7dffc2f92d3798f00a9d6bb84089624ebb70c8a3f5c4f1b7d666724392' 
  AND token = 'lk6MDRpKrDb2kKsq0m5aHdufi0tiHt0j6D6iXwKRFEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}