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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1629840b7a8b5b7257b89389c75e421e55a9d10c02ed139ba635ff81ffd3332a' 
  AND token = 'yFZZyY3nWGRuRItdtrQTBoUTw33nxqUI3hDX3pdpDW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}