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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f40226b34c0c62185cbfefb6449aab69b9118b46e58ce407f9393da2b05bd79' 
  AND token = 'nFrhibDKaaAcb8OKTAKHTEARxLsKB/qXXW3tkASytek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}