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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6714da52031444ab1f9f7edeb0a58c1fb409ebc1486b0aabbab8fda6860591' 
  AND token = 'VSAlUyeySo2XE9CQtl6ztcWvQJLtdhtZ68eUDM8CWU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}