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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b90cd165f6fdf837e93bfb558aeafd271ecd2d530a1ced012c9a441dc5bb1b66' 
  AND token = '3hq6leDhr1Cl5r9mbHVM1nkFuZKzB1jBSipFHlGwiAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}